发明授权
US07446174B2 Protein based TNF-α variants for the treatment of TNF-α related disorders
有权
用于治疗TNF-α相关疾病的基于蛋白质的TNF-α变体
- 专利标题： Protein based TNF-α variants for the treatment of TNF-α related disorders
- 专利标题（中）： 用于治疗TNF-α相关疾病的基于蛋白质的TNF-α变体
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申请号： US11108001申请日： 2005-04-14
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公开(公告)号： US07446174B2公开(公告)日： 2008-11-04
- 发明人: John R. Desjarlais , Paul Michael Steed , Jonathan Zalevsky , David Edmund Szymkowski
- 申请人： John R. Desjarlais , Paul Michael Steed , Jonathan Zalevsky , David Edmund Szymkowski
- 申请人地址： US CA Monrovia
- 专利权人： Xencor, Inc.
- 当前专利权人： Xencor, Inc.
- 当前专利权人地址： US CA Monrovia
- 代理机构： Morgan Lewis & Bockius LLP
- 代理商 Robin M. Silva, Esq.; David C. Foster, Esq.
- 主分类号： C07K17/00
- IPC分类号： C07K17/00 ; G01N33/53
摘要：
The invention relates to novel proteins with TNF-α antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNF-α related disorders.
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