发明授权
- 专利标题: Gamma-secretase inhibitors
- 专利标题(中): γ-分泌酶抑制剂
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申请号: US10566486申请日: 2004-07-29
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公开(公告)号: US07452899B2公开(公告)日: 2008-11-18
- 发明人: Michela Bettati , Amanda Louise Boase , Ian Churcher , Tamara Ladduwahetty , Kevin John Merchant , Abdul Quddus
- 申请人: Michela Bettati , Amanda Louise Boase , Ian Churcher , Tamara Ladduwahetty , Kevin John Merchant , Abdul Quddus
- 申请人地址: GB Hoddesdon, Hertfordshire
- 专利权人: Merck Sharp & Dohme Limited
- 当前专利权人: Merck Sharp & Dohme Limited
- 当前专利权人地址: GB Hoddesdon, Hertfordshire
- 代理商 William Krovatin; Raynard Yuro
- 优先权: GB0318447.0 20030805
- 国际申请: PCT/GB2004/003277 WO 20040729
- 国际公布: WO2005/014553 WO 20050217
- 主分类号: A01N43/42
- IPC分类号: A01N43/42 ; A01N47/00 ; A61K31/44 ; A61K31/21 ; A61K31/26 ; A61K43/64 ; C07D215/00 ; C07D217/00
摘要:
Compounds of Formula (I): inhibit the processing of APP by gamma-secretase, and hence are useful for treatment or prevention of Alzheimer's disease.
公开/授权文献
- US20060189666A1 Novel gamma-secretase inhibitors 公开/授权日:2006-08-24
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