发明授权
- 专利标题： ALK7 and myostatin inhibitors and uses thereof
- 专利标题（中）： ALK7和肌生成抑制素抑制剂及其用途
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申请号： US11071686申请日： 2005-03-02
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公开(公告)号： US07456149B2公开(公告)日： 2008-11-25
- 发明人: John Knopf , Jasbir Seehra
- 申请人： John Knopf , Jasbir Seehra
- 申请人地址： US MA Cambridge
- 专利权人： Acceleron Pharma, Inc.
- 当前专利权人： Acceleron Pharma, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Ropes & Gray LLP
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C12N15/11 ; C12N15/13
摘要：
The invention relates to ALK7 soluble receptors and their uses as antagonists of the function of certain ligands such as GDF-8 (Myostatin) and GDF-11. The ALK7 soluble receptor of the invention is useful as antagonists of GDF-8 and GDF-11 in the treatment of neuronal diseases or conditions such as stroke, spinal cord injury, and all peripheral nerve diseases. The ALK7 soluble receptor of the invention is also useful as GH (growth hormone) equivalent, and for increasing muscle mass.
公开/授权文献
- US20060030522A1 ALK7 and myostatin inhibitors and uses thereof 公开/授权日：2006-02-09
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