发明授权
- 专利标题: 5-aminoindole derivatives as H3 inverse agonists
- 专利标题(中): 5-氨基吲哚衍生物作为H3反向激动剂
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申请号: US11332955申请日: 2006-01-17
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公开(公告)号: US07456174B2公开(公告)日: 2008-11-25
- 发明人: Matthias Heinrich Nettekoven , Jean-Marc Plancher , Olivier Roche , Rosa Maria Rodriguez-Sarmiento
- 申请人: Matthias Heinrich Nettekoven , Jean-Marc Plancher , Olivier Roche , Rosa Maria Rodriguez-Sarmiento
- 申请人地址: US NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Nutley
- 代理商 George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- 优先权: EP05100312 20050119
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; C07D413/14
摘要:
The present invention relates to compounds of formula I wherein R1, R2, R3, R4 and m are as defined in the description and claims, and pharmaceutically acceptable salts thereof as well as to pharmaceutical compositions comprising these compounds and to methods for their preparation. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.
公开/授权文献
- US20060160855A1 5-Aminoindole derivatives as H3 inverse agonists 公开/授权日:2006-07-20