发明授权
- 专利标题： Hairpin polyamide
- 专利标题（中）： 发夹聚酰胺
-
申请号： US10507004申请日： 2003-03-03
-
公开(公告)号： US07456294B2公开(公告)日： 2008-11-25
- 发明人: Hiroshi Sugiyama , Toshikazu Bando , Isao Saito
- 申请人： Hiroshi Sugiyama , Toshikazu Bando , Isao Saito
- 申请人地址： JP Saitama
- 专利权人： Japan Science and Technology Agency
- 当前专利权人： Japan Science and Technology Agency
- 当前专利权人地址： JP Saitama
- 代理机构： Rader, Fishman & Grauer, PLLC
- 优先权： JP2002-063608 20020308
- 国际申请： PCT/JP03/02423 WO 20030303
- 国际公布： WO03/076412 WO 20030918
- 主分类号： A61K31/407
- IPC分类号： A61K31/407 ; C07D403/14
摘要：
It is intended to provide a pyrrole-imidazole polyamide type functional molecule having enhanced abilities of alkylating DNA and recognizing a sequence, compared with the existing functional molecules of this type, for a specific base sequence occurring on DNA. A hairpin polyamide having an alkylation site via a vinyl linker at the end of a pyrrole-imidazole polyamide. Drugs for inhibiting the expression of a specific gene and anticancer agents containing the above hairpin polyamide.
公开/授权文献
- US20050176647A1 Novel hairpin polyamide 公开/授权日：2005-08-11