发明授权
US07462627B2 Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
失效
用于治疗乳腺癌，结肠直肠癌，胰腺癌，卵巢癌和肺癌的7-乙基-10-羟基喜树碱的多臂聚合物缀合物
- 专利标题： Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
- 专利标题（中）： 用于治疗乳腺癌，结肠直肠癌，胰腺癌，卵巢癌和肺癌的7-乙基-10-羟基喜树碱的多臂聚合物缀合物
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申请号： US11704607申请日： 2007-02-09
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公开(公告)号： US07462627B2公开(公告)日： 2008-12-09
- 发明人: Hong Zhao , Maria Belen Rubio , Dechun Wu , Puja Sapra
- 申请人： Hong Zhao , Maria Belen Rubio , Dechun Wu , Puja Sapra
- 申请人地址： US NJ Bridgewater
- 专利权人： Enzon Pharmaceuticals, Inc.
- 当前专利权人： Enzon Pharmaceuticals, Inc.
- 当前专利权人地址： US NJ Bridgewater
- 代理机构： Lucas & Mercanti, LLP
- 主分类号： A61K31/4745
- IPC分类号： A61K31/4745 ; C07D491/22
摘要：
A four arm-polyethylene glycol-7-ethyl-10-hydroxycamptothecin conjugate, such as, is disclosed. Methods of making the conjugates and methods of treating mammals using the same are also disclosed.
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