发明授权
- 专利标题: Endonuclease-substrate complexes
- 专利标题(中): 内切核酸酶 - 底物复合物
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申请号: US10783557申请日: 2004-02-20
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公开(公告)号: US07482118B2公开(公告)日: 2009-01-27
- 发明人: Hatim T. Allawi , Michael W. Kaiser , Wu-Po Ma , Bruce P. Neri , Victor Lyamichev
- 申请人: Hatim T. Allawi , Michael W. Kaiser , Wu-Po Ma , Bruce P. Neri , Victor Lyamichev
- 申请人地址: US WI Madison
- 专利权人: Third Wave Technologies, Inc.
- 当前专利权人: Third Wave Technologies, Inc.
- 当前专利权人地址: US WI Madison
- 代理机构: Casimir Jones, S.C
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention provides novel cleavage agents for the cleavage and modification of nucleic acid. The cleavage agents find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, an endonuclease activity is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
公开/授权文献
- US20050048527A1 Endonuclease-substrate complexes 公开/授权日:2005-03-03
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