发明授权
- 专利标题: Arylpiperazinyl compounds
- 专利标题(中): 芳基哌嗪基化合物
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申请号: US11516345申请日: 2006-09-05
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公开(公告)号: US07491727B2公开(公告)日: 2009-02-17
- 发明人: Dale S. Dhanoa , Dongli Chen , Oren Becker , Silvia Noiman , Srinivasa R. Cheruku , Yael Marantz , Anurag Sharadendu , Sharon Shacham , Alexander Heifetz , Pradyumna Mohanty , Boaz Inbal , Merav Fichman , Raphael Nudelman , Shay Bar-Haim
- 申请人: Dale S. Dhanoa , Dongli Chen , Oren Becker , Silvia Noiman , Srinivasa R. Cheruku , Yael Marantz , Anurag Sharadendu , Sharon Shacham , Alexander Heifetz , Pradyumna Mohanty , Boaz Inbal , Merav Fichman , Raphael Nudelman , Shay Bar-Haim
- 申请人地址: US MA Lexington
- 专利权人: Epix Delaware, Inc.
- 当前专利权人: Epix Delaware, Inc.
- 当前专利权人地址: US MA Lexington
- 代理机构: Goodwin Procter LLP
- 主分类号: A61K31/495
- IPC分类号: A61K31/495 ; A61K31/496
摘要:
The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formula I, and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.
公开/授权文献
- US20070004742A1 Arylpiperazinyl compounds 公开/授权日:2007-01-04