Invention Grant
- Patent Title: RAF inhibitor compounds and methods
- Patent Title (中): RAF抑制剂化合物和方法
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Application No.: US11345828Application Date: 2006-02-02
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Publication No.: US07491829B2Publication Date: 2009-02-17
- Inventor: Ellen Laird , Joseph P. Lyssikatos , Mike Welch , Jonas Grina , Josh Hansen , Brad Newhouse , Alan Olivero , George Topalov
- Applicant: Ellen Laird , Joseph P. Lyssikatos , Mike Welch , Jonas Grina , Josh Hansen , Brad Newhouse , Alan Olivero , George Topalov
- Applicant Address: US CO Boulder US CA South San Francisco
- Assignee: Array Biopharma Inc.,Genentech, Inc.
- Current Assignee: Array Biopharma Inc.,Genentech, Inc.
- Current Assignee Address: US CO Boulder US CA South San Francisco
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: C07D231/14
- IPC: C07D231/14 ; A61K31/4155 ; A61K31/416
Abstract:
Pyrazolyl compounds of Formulas Ia and Ib are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using pyrazolyl compounds for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
Public/Granted literature
- US20060189627A1 RAF inhibitor compounds and methods Public/Granted day:2006-08-24
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