发明授权
US07494993B2 Amide derivatives of 7-amino-3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents
失效
7-氨基-3-苯基 - 二氢嘧啶并[4,5-d]嘧啶酮的酰胺衍生物，其制造和用作药剂
![Amide derivatives of 7-amino-3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents](/docs/US/2009-02-24/US07494993B2/abs.jpg.600x600.jpg)
- 专利标题： Amide derivatives of 7-amino-3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents
- 专利标题（中）： 7-氨基-3-苯基 - 二氢嘧啶并[4,5-d]嘧啶酮的酰胺衍生物，其制造和用作药剂
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申请号： US11660197申请日： 2005-08-30
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公开(公告)号： US07494993B2公开(公告)日： 2009-02-24
- 发明人: Richard Engh , Hubert Hertenberger , Konrad Honold , Birgit Masjost , Petra Rueger , Wolfgang Schaefer , Stefan Scheiblich , Manfred Schwaiger
- 申请人： Richard Engh , Hubert Hertenberger , Konrad Honold , Birgit Masjost , Petra Rueger , Wolfgang Schaefer , Stefan Scheiblich , Manfred Schwaiger
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; Gene J. Yao
- 优先权： EP04020597 20040831
- 国际申请： PCT/EP2005/009322 WO 20050830
- 国际公布： WO2006/024487 WO 20060309
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D487/04 ; A61K31/497 ; A61K31/519 ; A61K31/5355
![Amide derivatives of 7-amino-3-phenyl-dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents](/abs-image/US/2009/02/24/US07494993B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to novel amide derivatives of 7-amino-3-phenyl dihydropyrimido[4,5-d]pyrimidinones, to a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. The present derivatives are new compounds of the general formula (I).
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