发明授权
- 专利标题: Spiroindolinone derivatives
- 专利标题(中): 螺吲哚啉酮衍生物
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申请号: US11846597申请日: 2007-08-29
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公开(公告)号: US07495007B2公开(公告)日: 2009-02-24
- 发明人: Li Chen , Qingjie Ding , Jin-Jun Liu , Song Yang , Zhuming Zhang
- 申请人: Li Chen , Qingjie Ding , Jin-Jun Liu , Song Yang , Zhuming Zhang
- 申请人地址: US NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni
- 主分类号: A61K31/438
- IPC分类号: A61K31/438 ; C07D471/10
摘要:
The present invention relates to spiroindolinone derivatives of the formula and their enantiomers and pharmaceutically acceptable salts and esters thereof wherein R1, R2, R3, R4, R5, R6, R7 and R8, are as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer agents.
公开/授权文献
- US20080009486A1 SPIROINDOLINONE DERIVATIVES 公开/授权日:2008-01-10
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