A manifold and filter assembly for use with a waste collection unit is provided. The manifold and filter assembly directs and filters medical waste flowing into the waste collection unit. The manifold and filter assembly comprises a manifold body defining a chamber and an outlet for directing the medical waste into the waste collection unit. A manifold cap is fitted to the manifold body to close the chamber. The manifold cap defines a plurality of inlets for receiving the medical waste. A filter basket having a bottom and a peripheral wall defining a plurality of openings is snap-locked to the manifold body. The filter basket is positioned such that a fluid bypass is formed between the filter basket and the manifold body and between the filter basket and the manifold cap. The fluid bypass is in fluid communication with the outlet whereby the medical waste can flow over the peripheral wall to the outlet through the fluid bypass.