发明授权
- 专利标题: Dosage form and method for producing the same
- 专利标题(中): 用途及其制备方法
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申请号: US10512860申请日: 2004-03-02
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公开(公告)号: US07498044B2公开(公告)日: 2009-03-03
- 发明人: Hans-Ulrich Petereit , Christian Meier , Klaus Schultes
- 申请人: Hans-Ulrich Petereit , Christian Meier , Klaus Schultes
- 申请人地址: DE Darmstadt
- 专利权人: Roehm GmbH & Co. KG
- 当前专利权人: Roehm GmbH & Co. KG
- 当前专利权人地址: DE Darmstadt
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权: DE10319458 20030429
- 国际申请: PCT/EP2004/002061 WO 20040302
- 国际公布: WO2004/096185 WO 20041111
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; A61K9/16 ; A61K9/20 ; A61K9/48
摘要:
The invention relates to a process for producing a coated drug form or a drug form in the form of an active ingredient matrix, by processing a copolymer, an active pharmaceutical ingredient, a core if present and/or pharmaceutically customary excipients in a conventional manner by melting, injection molding, extrusion, wet granulation, casting, dipping, spreading, spraying or compression to form a coated drug form and/or to form an active ingredient matrix, characterized in that a copolymer is used which is composed of 20 to 33% by weight methacrylic acid, 5 to 30% by weight methyl acrylate, 20 to 40% by weight ethyl acrylate and more than 10 to 30% by weight butyl methacrylate and, if desired, 0 to 10% by weight further vinylically copolymerizable monomers, with the proviso that the glass transition temperature of the copolymer in accordance with ISO 11357-2, section 3.3.3, is 55 to 70° C. The invention further relates to the drug form produced in accordance with the invention, to the copolymer, and to the use thereof.
公开/授权文献
- US20050152977A1 Dosage form and method for producing the same 公开/授权日:2005-07-14
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