Invention Grant
US07511124B2 Compositions comprising phosphatidylethanolamine-binding peptides linked to anti-viral agents
有权
包含与抗病毒剂连接的磷脂酰乙醇胺结合肽的组合物
- Patent Title: Compositions comprising phosphatidylethanolamine-binding peptides linked to anti-viral agents
- Patent Title (中): 包含与抗病毒剂连接的磷脂酰乙醇胺结合肽的组合物
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Application No.: US10642121Application Date: 2003-08-15
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Publication No.: US07511124B2Publication Date: 2009-03-31
- Inventor: Philip E. Thorpe , M. Melina Soares , Jin He
- Applicant: Philip E. Thorpe , M. Melina Soares , Jin He
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Shelley P. M. Fussey
- Main IPC: C07K14/00
- IPC: C07K14/00 ; A61K31/00
Abstract:
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
Public/Granted literature
- US20050059578A1 Compositions comprising phosphatidylethanolamine-binding peptides linked to anti-viral agents Public/Granted day:2005-03-17
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