发明授权
- 专利标题: Azabicyclic aryl derivatives
- 专利标题(中): 偶氮二芳基衍生物
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申请号: US10591871申请日: 2005-05-10
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公开(公告)号: US07514450B2公开(公告)日: 2009-04-07
- 发明人: Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Tino Dyhring Jørgensen , Daniel B. Timmermann
- 申请人: Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Tino Dyhring Jørgensen , Daniel B. Timmermann
- 申请人地址: DK Ballerup
- 专利权人: NeuroSearch A/S
- 当前专利权人: NeuroSearch A/S
- 当前专利权人地址: DK Ballerup
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: DK200400799 20040519
- 国际申请: PCT/EP2005/052107 WO 20050510
- 国际公布: WO2005/111033 WO 20051124
- 主分类号: A01N43/90
- IPC分类号: A01N43/90 ; A61K31/44 ; C07D453/02
摘要:
This invention relates to novel azabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
公开/授权文献
- US20070203117A1 Novel Azabicyclic Aryl Derivatives 公开/授权日:2007-08-30