发明授权
- 专利标题： Peptide and a derivative thereof promoting cell adhesion and spreading
- 专利标题（中）： 肽及其衍生物促进细胞粘附和扩散
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申请号： US10555590申请日： 2005-07-08
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公开(公告)号： US07517654B2公开(公告)日： 2009-04-14
- 发明人: Byung-Moo Min , Jin-Man Kim
- 申请人： Byung-Moo Min , Jin-Man Kim
- 申请人地址： KR Seoul
- 专利权人： Seoul National University Industry Foundation
- 当前专利权人： Seoul National University Industry Foundation
- 当前专利权人地址： KR Seoul
- 代理机构： Intellectual Property/Technology Law
- 代理商 Kelly Reynolds; Steven J. Hultquist
- 优先权： KR10-2004-0069941 20040902
- 国际申请： PCT/KR2005/002205 WO 20050708
- 国际公布： WO2006/025646 WO 20060309
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K38/04 ; A61K39/00 ; A61K38/00
摘要：
The present invention relates to a peptide promoting cell adhesion and spreading, fragments, and derivatives thereof, more particularly, integrin-α3β1-dependent peptide in human laminin-5 α3 chain LG3 domain, mediating integrin α3β1 binding and cell adhesion and spreading, fragments and derivatives thereof. The inventive peptide, fragments and derivatives thereof can be used effectively for research on cell adhesion activity, wound care, tissue regeneration, inhibition of cancer metastesis etc. mediated by various extracellular matrix protein including laminin.
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