发明授权
US07531660B2 1-[[1-[(2-amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl]carbonyl]-4-[2-(2-pyridinyl)-3H-imidazo[4,5-B]pyridin-3-YL]piperidine and methods of use thereof
失效
1 - [[1 - [(2-氨基-6-甲基-4-吡啶基)甲基] -4-氟-4-哌啶基]羰基] -4- [2-(2-吡啶基)-3H-咪唑并[4 ,5-B]吡啶-3-YL]哌啶及其使用方法
- 专利标题: 1-[[1-[(2-amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl]carbonyl]-4-[2-(2-pyridinyl)-3H-imidazo[4,5-B]pyridin-3-YL]piperidine and methods of use thereof
- 专利标题(中): 1 - [[1 - [(2-氨基-6-甲基-4-吡啶基)甲基] -4-氟-4-哌啶基]羰基] -4- [2-(2-吡啶基)-3H-咪唑并[4 ,5-B]吡啶-3-YL]哌啶及其使用方法
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申请号: US11837248申请日: 2007-08-10
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公开(公告)号: US07531660B2公开(公告)日: 2009-05-12
- 发明人: Manuel de Lera Ruiz , Robert G. Aslanian , Michael Y. Berlin , Kevin D. McCormick , Chander S. Celly
- 申请人: Manuel de Lera Ruiz , Robert G. Aslanian , Michael Y. Berlin , Kevin D. McCormick , Chander S. Celly
- 申请人地址: US NJ Kenilworth
- 专利权人: Schering Corporation
- 当前专利权人: Schering Corporation
- 当前专利权人地址: US NJ Kenilworth
- 代理商 Jeffrey P. Bergman
- 主分类号: C07D498/02
- IPC分类号: C07D498/02 ; A01N43/42
摘要:
The present invention discloses the compound of Formula I and pharmaceutically acceptable salts and solvates thereof. The invention also relates to pharmaceutical compositions comprising the Compound of Formula I and its use in treating obesity, metabolic syndrome, diabetes, hepatic lipidosis or nonalcoholic fatty liver disease. The invention also relates to the use of a combination of the Compound of Formula I with additional therapeutic agents for treating obesity, metabolic syndrome, diabetes, hepatic lipidosis or nonalcoholic fatty liver disease.
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