- 专利标题: Attenuation of cytomegalovirus virulence
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申请号: US11613501申请日: 2006-12-20
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公开(公告)号: US07537770B2公开(公告)日: 2009-05-26
- 发明人: George Kemble , Gregory M. Duke , Richard Spaete
- 申请人: George Kemble , Gregory M. Duke , Richard Spaete
- 申请人地址: US MD Gaithersburg
- 专利权人: MedImmune, LLC
- 当前专利权人: MedImmune, LLC
- 当前专利权人地址: US MD Gaithersburg
- 主分类号: A61K39/12
- IPC分类号: A61K39/12 ; A61K39/245 ; C12Q1/70
摘要:
A method is provided for attenuating a cytomegalovirus comprising functionally disrupting an open reading frame of a Toledo genome region or its homolog and making chimeric CMV virus genomes.
公开/授权文献
- US20080019945A1 Attenuation of Cytomegalovirus Virulence 公开/授权日:2008-01-24
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