发明授权
- 专利标题： Microwave mediated synthesis of nucleic acid probes
- 专利标题（中）： 微波介导的核酸探针合成
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申请号： US11018897申请日： 2004-12-21
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公开(公告)号： US07541455B2公开(公告)日： 2009-06-02
- 发明人: Christopher Bieniarz , Michael Farrell , Jerome W. Kosmeder , Mark Lefever
- 申请人： Christopher Bieniarz , Michael Farrell , Jerome W. Kosmeder , Mark Lefever
- 申请人地址： US AZ Tucson
- 专利权人： Ventana Medical Systems, Inc.
- 当前专利权人： Ventana Medical Systems, Inc.
- 当前专利权人地址： US AZ Tucson
- 代理机构： Ventana Medicals Systems, Inc.
- 代理商 Aden A. Rehms
- 主分类号： C07H21/02
- IPC分类号： C07H21/02 ; C07H21/04 ; C12Q1/68
摘要：
A method for preparing a nucleic acid probe is provided. The method comprises forming an activated cytosine or cytidine by a bisulfite catalyzed reaction; and covalently linking a reporter molecule to the activated cytosine or cytidine, wherein said activating step, said covalently linking step, or both are conducted in the presence of microwave energy. Also provided by the invention are nucleic acid probes.
公开/授权文献
- US20050158770A1 Microwave mediated synthesis of nucleic acid probes 公开/授权日：2005-07-21
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