Invention Grant
- Patent Title: 2-amino- and 2-thio- substituted 1,3-diaminopropanes
- Patent Title (中): 2-氨基和2-硫代取代的1,3-二氨基丙烷
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Application No.: US11090520Application Date: 2005-03-25
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Publication No.: US07544717B2Publication Date: 2009-06-09
- Inventor: Roy Hom , John Tucker , Varghese John , Neerav Shah
- Applicant: Roy Hom , John Tucker , Varghese John , Neerav Shah
- Applicant Address: US CA South San Francisco
- Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee: Elan Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K31/165
- IPC: A61K31/165 ; A61K31/18 ; C07C233/36 ; C07C311/05
Abstract:
Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.
Public/Granted literature
- US20050267199A1 2-Amino- and 2-thio- substituted 1,3-diaminopropanes Public/Granted day:2005-12-01
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