发明授权
US07550155B2 Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
有权
2,6-二异丙基苯酚（丙泊酚）的水性药物组合物及其用途
- 专利标题： Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
- 专利标题（中）： 2,6-二异丙基苯酚（丙泊酚）的水性药物组合物及其用途
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申请号： US10766631申请日： 2004-01-28
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公开(公告)号： US07550155B2公开(公告)日： 2009-06-23
- 发明人: Zhong Zhang , Orn Almarsson , Hongming Chen
- 申请人： Zhong Zhang , Orn Almarsson , Hongming Chen
- 申请人地址： US MA Lexington
- 专利权人： Transform Pharmaceuticals Inc.
- 当前专利权人： Transform Pharmaceuticals Inc.
- 当前专利权人地址： US MA Lexington
- 代理机构： RatnerPrestia PC
- 优先权： WOPCT/US03/23512 20030729; WOPCT/US03/31086 20031002
- 主分类号： A61K9/14
- IPC分类号： A61K9/14
摘要：
The present invention provides aqueous pharmaceutical compositions containing a lipophilic therapeutic agent. In particular, the invention provides aqueous pharmaceutical compositions containing the compound 2,6-diisopropylphenol (propofol). Preferred compositions of the invention contain propofol in the presence of at least one block copolymer (for example, P188 or another poloxamer) and a polyethylene glycol (PEG). Compositions of the invention are preferably sterile or are readily sterilized (e.g., by autoclaving) and are suitable for parenteral administration to any animal, including humans. The compositions are also chemically and physically stable over a wide range of environmental conditions and for extended periods of time.
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