Invention Grant
- Patent Title: Mitotic kinesin inhibitors
- Patent Title (中): 有丝分裂驱动蛋白抑制剂
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Application No.: US11630302Application Date: 2005-06-27
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Publication No.: US07553838B2Publication Date: 2009-06-30
- Inventor: Mark E. Fraley , George D. Hartman
- Applicant: Mark E. Fraley , George D. Hartman
- Applicant Address: US NJ Rahway
- Assignee: Merck & Co. Inc.
- Current Assignee: Merck & Co. Inc.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; David A. Muthard
- International Application: PCT/US2005/023012 WO 20050627
- International Announcement: WO2006/007501 WO 20060119
- Main IPC: C07D403/06
- IPC: C07D403/06 ; C07D403/14 ; A61K31/496
Abstract:
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Public/Granted literature
- US20080032980A1 Mitotic Kinesin Inhibitors Public/Granted day:2008-02-07
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