发明授权
US07553881B2 Dental materials based on radically polymerizable macromers with antimicrobial effect
有权
基于可自由基聚合的大分子单体的牙科材料具有抗菌作用
- 专利标题: Dental materials based on radically polymerizable macromers with antimicrobial effect
- 专利标题(中): 基于可自由基聚合的大分子单体的牙科材料具有抗菌作用
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申请号: US11502420申请日: 2006-08-11
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公开(公告)号: US07553881B2公开(公告)日: 2009-06-30
- 发明人: Ulrich Salz , Jörg Zimmermann , Dirk Poppe , Volker Rheinberger , Jörg Tiller , Christian Waschinski
- 申请人: Ulrich Salz , Jörg Zimmermann , Dirk Poppe , Volker Rheinberger , Jörg Tiller , Christian Waschinski
- 申请人地址: LI Schaan
- 专利权人: Ivoclar Vivadent AG
- 当前专利权人: Ivoclar Vivadent AG
- 当前专利权人地址: LI Schaan
- 代理机构: Nixon Peabody LLP
- 优先权: EP06113260 20060428
- 主分类号: A61K6/083
- IPC分类号: A61K6/083 ; C08F26/06
摘要:
Dental material which contains at least one compound of the formula [PG]m—R1—Z—SP—Y—R2—[WG]p, in which m=1, 2 or 3; p=1, 2 or 3; R1=is absent, a linear or branched C1 to C20 alkylene radical which can be interrupted one or more times by O, S, NH, SiR′, CONH CONR′, COO and/or OCONH, a substituted or unsubstituted, aromatic C6 to C14 radical or a combination thereof R2=is absent, a linear or branched C1 to C20 alkylene radical which can be interrupted one or more times by O, S, NH, SiR′, CONH CONR′, COO and/or OCONH, a substituted or unsubstituted, aromatic C6 to C14 radical or a combination thereof; PG=a radically polymerizable group; SP=a polymeric spacer which is selected from polyethylene glycol, polypropylene glycol, polyglycerol, polyalkyloxazoline, polyethyleneimine, polyacrylic acid, polymethacrylic acid, polyvinyl alcohol, polyvinyl acetate, poly-(2-hydroxyethyl)acrylate, poly-(2-hydroxyethyl)methacrylate groups, hydrophilic polypeptide groups and copolymers of the corresponding monomers; WG=antimicrobially active group; Z=is absent, O, S, an ester, amide or urethane group; Y=is absent, O, S, an ester, amide or urethane group, and which has a molecular weight of at least 1,000.
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