发明授权
- 专利标题： Attenuated dengue virus comprising mutations in the NS3 gene
- 专利标题（中）： 减毒的登革热病毒包含NS3基因突变
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申请号： US11446050申请日： 2006-06-02
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公开(公告)号： US07560118B2公开(公告)日： 2009-07-14
- 发明人: Stephen S. Whitehead , Brian R. Murphy , Kathryn A. Hanley , Joseph E. Blaney
- 申请人： Stephen S. Whitehead , Brian R. Murphy , Kathryn A. Hanley , Joseph E. Blaney
- 申请人地址： US DC Washington
- 专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Knobbe Martens Olson & Bear LLP
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; C12N7/04
摘要：
A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.
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