- 专利标题: Diarylamine-containing compounds and compositions, and their use as modulators of c-kit receptors
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申请号: US11932945申请日: 2007-10-31
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公开(公告)号: US07563894B2公开(公告)日: 2009-07-21
- 发明人: Valentina Molteni , Shuli You , Juliet Nabakka , Yi Liu , Xiaolin Li , Donatella Chianelli , Jon Loren , Xiaodong Liu , Shifeng Pan , Donald S. Karanewsky , Pascal Furet , Vito Guagnano
- 申请人: Valentina Molteni , Shuli You , Juliet Nabakka , Yi Liu , Xiaolin Li , Donatella Chianelli , Jon Loren , Xiaodong Liu , Shifeng Pan , Donald S. Karanewsky , Pascal Furet , Vito Guagnano
- 申请人地址: BM Hamilton CH Basel
- 专利权人: IRM LLC,Novartis AG
- 当前专利权人: IRM LLC,Novartis AG
- 当前专利权人地址: BM Hamilton CH Basel
- 代理机构: Genomics Institute of the Novartis Research Foundation
- 代理商 Daniel E. Raymond
- 主分类号: C07D403/10
- IPC分类号: C07D403/10 ; C07D403/14 ; C07D239/42 ; A61K31/505
摘要:
Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.