发明授权
![Substituted thienol[2,3-d]pyrimidines as kinase inhibitors](/docs/US/2009-07-28/US07566721B2/abs.jpg.600x600.jpg)
- 专利标题： Substituted thienol[2,3-d]pyrimidines as kinase inhibitors
- 专利标题（中）： 取代的噻吩并[2,3-d]嘧啶作为激酶抑制剂
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申请号： US11498975申请日： 2006-08-03
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公开(公告)号： US07566721B2公开(公告)日： 2009-07-28
- 发明人: Qun-Sheng Ji , Mark Joseph Mulvihill , Arno G. Steinig , Qinghua Weng
- 申请人： Qun-Sheng Ji , Mark Joseph Mulvihill , Arno G. Steinig , Qinghua Weng
- 申请人地址： US NY Melville
- 专利权人： OSI Pharmaceuticals, Inc.
- 当前专利权人： OSI Pharmaceuticals, Inc.
- 当前专利权人地址： US NY Melville
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D495/04 ; A61P35/04 ; A61P31/22 ; A61P11/06 ; A61P19/02
![Substituted thienol[2,3-d]pyrimidines as kinase inhibitors](/abs-image/US/2009/07/28/US07566721B2/abs.jpg.150x150.jpg)
摘要：
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.