发明授权
- 专利标题： Salts of potassium ATP channel openers and uses thereof
- 专利标题（中）： 钾ATP通道开放剂的盐及其用途
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申请号： US12391990申请日： 2009-02-24
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公开(公告)号： US07572789B2公开(公告)日： 2009-08-11
- 发明人: Neil M. Cowen , Kenneth B. Kashkin , Khaled A. Yamout
- 申请人： Neil M. Cowen , Kenneth B. Kashkin , Khaled A. Yamout
- 申请人地址： US CA Carlsbad
- 专利权人： Essentialis, Inc.
- 当前专利权人： Essentialis, Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Foley & Lardner LLP
- 主分类号： A61K31/549
- IPC分类号： A61K31/549 ; C07D285/22
摘要：
Provided are immediate or prolonged administration of certain salts of KATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are method of co-administering the salts with other drugs to treat diseases of humans and animals.
公开/授权文献
- US20090148526A1 SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF 公开/授权日：2009-06-11
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