发明授权
US07582281B2 Ethylenedicysteine (EC)-drug conjugates compositions and methods for tissue specific disease imaging
有权
亚乙基半胱氨酸（EC） - 药物共轭物组织特异性疾病成像的组合物和方法
- 专利标题： Ethylenedicysteine (EC)-drug conjugates compositions and methods for tissue specific disease imaging
- 专利标题（中）： 亚乙基半胱氨酸（EC） - 药物共轭物组织特异性疾病成像的组合物和方法
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申请号： US11627299申请日： 2007-01-25
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公开(公告)号： US07582281B2公开(公告)日： 2009-09-01
- 发明人: David J. Yang , Chun W. Liu , Dong-Fang Yu , E. Edmund Kim
- 申请人： David J. Yang , Chun W. Liu , Dong-Fang Yu , E. Edmund Kim
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： US TX Austin
- 代理机构： Fulbright & Jaworski LLP
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; A61M36/14
摘要：
The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
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