发明授权
US07582638B2 Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors
失效
吡唑 - 异喹啉脲衍生物作为p38激酶抑制剂
- 专利标题: Pyrazole-isoquinoline urea derivatives as p38 kinase inhibitors
- 专利标题(中): 吡唑 - 异喹啉脲衍生物作为p38激酶抑制剂
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申请号: US12089420申请日: 2006-10-23
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公开(公告)号: US07582638B2公开(公告)日: 2009-09-01
- 发明人: Alfonso De Dios , Cristina Garcia-Paredes , Beatriz López de Uralde Garmendia , Mary Margaret Mader , Mark Andrew Pobanz , Chuan Shih , Boyu Zhong
- 申请人: Alfonso De Dios , Cristina Garcia-Paredes , Beatriz López de Uralde Garmendia , Mary Margaret Mader , Mark Andrew Pobanz , Chuan Shih , Boyu Zhong
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 代理商 Tina M Tucker; Tonya Combs
- 优先权: EP05380240 20051028; EP06380097 20060426
- 国际申请: PCT/US2006/041266 WO 20061023
- 国际公布: WO2007/053346 WO 20071005
- 主分类号: A61K31/4725
- IPC分类号: A61K31/4725 ; A61K31/496 ; C07D403/141
摘要:
The present invention provides kinase inhibitors of Formula (I) wherein R1, R2, and X are as described herein, or a pharmaceutically acceptable salt thereof.
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