发明授权
- 专利标题: Water-soluble strontium salts for use in treatment of cartilage and/or bone conditions
- 专利标题(中): 用于治疗软骨和/或骨骼状况的水溶性锶盐
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申请号: US11269289申请日: 2005-11-07
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公开(公告)号: US07595342B2公开(公告)日: 2009-09-29
- 发明人: Christian Hansen , Henrik Nilsson , Stephan Christgau , Jens E.T. Andersen
- 申请人: Christian Hansen , Henrik Nilsson , Stephan Christgau , Jens E.T. Andersen
- 申请人地址: DK Copenhagen O
- 专利权人: Osteologix A/S
- 当前专利权人: Osteologix A/S
- 当前专利权人地址: DK Copenhagen O
- 代理机构: Jones Day
- 优先权: DK200300691 20030507; DK200300932 20030620; DK200301820 20031209
- 主分类号: A61K31/19
- IPC分类号: A61K31/19
摘要:
Compounds and pharmaceutical compositions for use in the treatment and/or prophylaxis of cartilage and/or bone conditions and for methods of treating such condition. The compounds are salts of strontium that have a water-solubility of from about 1 g/l to about 100 g/l at room temperature, especially amino acid salts of strontium or dicarboxylic acid salts of strontium. Examples of novel water-soluble strontium salts are e.g. strontium glutamate and strontium alpha-ketoglutarate. The present invention also relates to an improved method for preparing the strontium salt of glutamic acid.
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