发明授权
- 专利标题: Use of prion conversion modulating agents
- 专利标题(中): 使用朊病毒转化调节剂
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申请号: US10560978申请日: 2004-06-18
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公开(公告)号: US07598046B2公开(公告)日: 2009-10-06
- 发明人: Claudio Soto-Jara , Kinsey Maundrell
- 申请人: Claudio Soto-Jara , Kinsey Maundrell
- 申请人地址: CH Coinsins
- 专利权人: Laboratories Serono SA
- 当前专利权人: Laboratories Serono SA
- 当前专利权人地址: CH Coinsins
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权: EP03101795 20030619
- 国际申请: PCT/EP2004/051170 WO 20040618
- 国际公布: WO2004/111652 WO 20041223
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; A61K49/00 ; A61K39/395 ; A61K39/00
摘要:
The use of Apolipoprotein B, Apolipoprotein E, fragments and mimetics thereof is provided for diagnostic, detection, prognostic and therapeutic applications In prion diseases. More specifically, the invention provides the use of Apolipoprotein B or fragments thereof for modulating or identifying modulators of the prion protein replication which are implicated in the pathogenesis of transmissible spongiform encephalopathics and other prion diseases.
公开/授权文献
- US20070020682A1 Use of prion conversion modulating agents 公开/授权日:2007-01-25
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