发明授权
US07598248B2 Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols, compositions thereof, and methods for their use
有权
某些1H-咪唑并[4,5-b]吡嗪-2(3H) - 酮和1H-咪唑并[4,5-b]吡嗪-2-醇,其组合物及其使用方法
- 专利标题: Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols, compositions thereof, and methods for their use
- 专利标题(中): 某些1H-咪唑并[4,5-b]吡嗪-2(3H) - 酮和1H-咪唑并[4,5-b]吡嗪-2-醇,其组合物及其使用方法
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申请号: US11888902申请日: 2007-08-01
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公开(公告)号: US07598248B2公开(公告)日: 2009-10-06
- 发明人: Alex Muci , Jeffrey T. Finer , Pu-Ping Lu , Alan James Russell , Bradley P. Morgan , David J. Morgans, Jr.
- 申请人: Alex Muci , Jeffrey T. Finer , Pu-Ping Lu , Alan James Russell , Bradley P. Morgan , David J. Morgans, Jr.
- 申请人地址: US CA South San Francisco
- 专利权人: Cytokinetics, Inc.
- 当前专利权人: Cytokinetics, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 主分类号: A61K31/497
- IPC分类号: A61K31/497
摘要:
Provided is at least one chemical entity chosen from compounds of Formula I and compounds of Formula II: and pharmaceutically acceptable salts thereof, compositions thereof, and methods for their use in modulating of one or more of skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, skeletal muscle, and skeletal sarcomere.
公开/授权文献
- US20080146561A1 Certain chemical entities, compositions and methods 公开/授权日:2008-06-19
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