发明授权
- 专利标题: Thienopyrimidines useful as Aurora kinase inhibitors
- 专利标题(中): 噻吩并嘧啶可用作极光激酶抑制剂
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申请号: US11182215申请日: 2005-07-15
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公开(公告)号: US07601725B2公开(公告)日: 2009-10-13
- 发明人: Willard Lew , Subramanian Baskaran , Johan D. Oslob , Joshua C. Yoburn , Min Zhong
- 申请人: Willard Lew , Subramanian Baskaran , Johan D. Oslob , Joshua C. Yoburn , Min Zhong
- 申请人地址: US CA South San Francisco
- 专利权人: Sunesis Pharmaceuticals, Inc.
- 当前专利权人: Sunesis Pharmaceuticals, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: Choate Hall & Stewart, LLP
- 代理商 Andrea L. C. Robidoux
- 主分类号: A01N43/90
- IPC分类号: A01N43/90 ; A61K31/519 ; C07D491/00 ; C07D495/00
摘要:
The present invention provides compounds having the formula: wherein R1, R2, X1, X2, L1, L2, Y and Z are as defined in classes and subclasses herein, and pharmaceutical compositions thereof, as described generally and in subclasses herein, which compounds are useful as inhibitors of protein kinase (e.g., Aurora), and thus are useful, for example, for the treatment of Aurora mediated diseases.
公开/授权文献
- US20060035908A1 Thienopyrimidines useful as Aurora kinase inhibitors 公开/授权日:2006-02-16
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