发明授权
- 专利标题: Cyclic amine compound
- 专利标题(中): 环胺化合物
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申请号: US11578169申请日: 2005-04-08
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公开(公告)号: US07601734B2公开(公告)日: 2009-10-13
- 发明人: Toshihito Kumagai , Toshio Nakamura , Yuri Amada , Yoshinori Sekiguchi
- 申请人: Toshihito Kumagai , Toshio Nakamura , Yuri Amada , Yoshinori Sekiguchi
- 申请人地址: JP Tokyo
- 专利权人: Taisho Pharmaceutical Co., Ltd.
- 当前专利权人: Taisho Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2004-116599 20040412
- 国际申请: PCT/JP2005/007278 WO 20050408
- 国际公布: WO2005/100355 WO 20051027
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61P25/18 ; A61P25/24
摘要:
An object of the present invention is to provide a cyclic amine compound which has a potent inhibitory effect on the binding of α2C-adrenoceptor and is useful in preventing and treating disorders attributable to α2C-adrenoceptor.The above-described object is solved by the following cyclic amine compound, etc., wherein X is O, S, SO, SO2 or NR2, etc.; R1 is a hydrogen atom, a cyano group, a carboxyl group, a C2-C13 alkoxycarbonyl group, a carbamoyl group, etc.; Ar1 and Ar2 are the same or different and each represent an aryl or heteroaryl group which may be substituted by 1 to 3 substituents and so on; ring B is a benzene ring may be substituted by 1 to 3 substituents and so on; n is an integer from 1 to 10; and p and q are the same or different and each represent an integer of 1 or 2.
公开/授权文献
- US20070244145A1 Cyclic Amine Compound 公开/授权日:2007-10-18
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