Invention Grant
US07605155B2 Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
有权
取代的吡唑并[1,5-a]嘧啶作为蛋白激酶抑制剂
![Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors](/docs/US/2009-10-20/US07605155B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
- Patent Title (中): 取代的吡唑并[1,5-a]嘧啶作为蛋白激酶抑制剂
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Application No.: US11542920Application Date: 2006-10-04
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Publication No.: US07605155B2Publication Date: 2009-10-20
- Inventor: Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer , Marc Labroli , Kartik M. Keertikar
- Applicant: Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer , Marc Labroli , Kartik M. Keertikar
- Applicant Address: US NJ Kenilworth
- Assignee: Schering Corporation
- Current Assignee: Schering Corporation
- Current Assignee Address: US NJ Kenilworth
- Agent Palaiyur S. Kalyanaraman
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D413/06 ; C07D417/04 ; C07D243/08 ; A61K31/519 ; A61K31/551 ; A61K31/497 ; A61K31/541 ; A61K31/5355 ; A61P35/04
![Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors](/abs-image/US/2009/10/20/US07605155B2/abs.jpg.150x150.jpg)
Abstract:
In its many embodiments, the present invention provides a class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases (CDKs), methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. All illustrative compound is shown below:
Public/Granted literature
- US20070072881A1 Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors Public/Granted day:2007-03-29
Information query
