A droplet generation apparatus is applied to a nebulizer. The droplet generation apparatus comprises a vibratable member, a nozzle disc, a housing and a connection member or a fastening plate or both the connection member and the fastening plate. The vibratable member has a first through hole. The nozzle disc has a plurality of apertures facing the first through hole, and is combined with the vibratable member. The connection member is disposed between the vibratable member and the nozzle disc, and has a second through hole corresponding to the first through hole. Alternatively, the fastening plate is combined with the nozzle disc. The housing covers up the combination of the vibratable member, the nozzle disc and the connection member or the fastening plate. Vibration efficiency generated by the vibratable member is improved through the connection member. An accommodation space is formed by the fastening plate and the nozzle disc.