Invention Grant
US07612207B2 Method for preparing clopidogrel 1,5-naphthalenedisulfonate or hydrate thereof
失效
制备1,5-萘二磺酸氯吡格雷或其水合物的方法
- Patent Title: Method for preparing clopidogrel 1,5-naphthalenedisulfonate or hydrate thereof
- Patent Title (中): 制备1,5-萘二磺酸氯吡格雷或其水合物的方法
-
Application No.: US12293959Application Date: 2007-03-16
-
Publication No.: US07612207B2Publication Date: 2009-11-03
- Inventor: Kwee Hyun Suh , Sang Min Yun , Eun Sook Kim , Gwan Sun Lee
- Applicant: Kwee Hyun Suh , Sang Min Yun , Eun Sook Kim , Gwan Sun Lee
- Applicant Address: KR Hwaseong-gun
- Assignee: Hanmi Pharm. Co., Ltd.
- Current Assignee: Hanmi Pharm. Co., Ltd.
- Current Assignee Address: KR Hwaseong-gun
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: KR10-2006-0026110 20060322
- International Application: PCT/KR2007/001307 WO 20070316
- International Announcement: WO2007/108615 WO 20070927
- Main IPC: C07D495/04
- IPC: C07D495/04
Abstract:
The present invention relates to a method for preparing clopidogrel 1,5-naphthalenedisulfonate or a hydrate thereof, which comprises reacting a clopidogrel-acid addition salt with disodium 1,5-naphthalenedisulfonate or its hydrate in water, or a mixture of water and an organic solvent. High quality clopidogrel 1,5-naphthalenedisulfonate can be prepared by the inventive method by way of using non-corrosive disodium 1,5-naphthalenedisulfonate.
Public/Granted literature
- US20090036683A1 METHOD FOR PREPARING CLOPIDOGREL 1,5-NAPHTHALENEDISULFONATE OR HYDRATE THEREOF Public/Granted day:2009-02-05
Information query
