发明授权
US07618975B2 4-arylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
有权
4-芳基氨基 - 喹唑啉和类似物作为胱天蛋白酶的激活剂和凋亡诱导剂及其用途
- 专利标题: 4-arylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
- 专利标题(中): 4-芳基氨基 - 喹唑啉和类似物作为胱天蛋白酶的激活剂和凋亡诱导剂及其用途
-
申请号: US10885903申请日: 2004-07-06
-
公开(公告)号: US07618975B2公开(公告)日: 2009-11-17
- 发明人: Sui Xiong Cai , Nilantha Sudath Sirisoma , Azra Pervin , John A. Drewe , Shailaja Kasibhatla , Songchun Jiang , Hong Zhang , Chris Pleiman
- 申请人: Sui Xiong Cai , Nilantha Sudath Sirisoma , Azra Pervin , John A. Drewe , Shailaja Kasibhatla , Songchun Jiang , Hong Zhang , Chris Pleiman
- 申请人地址: US UT Salt Lake City US CA San Diego
- 专利权人: Myriad Pharmaceuticals, Inc.,Cytovia, Inc.
- 当前专利权人: Myriad Pharmaceuticals, Inc.,Cytovia, Inc.
- 当前专利权人地址: US UT Salt Lake City US CA San Diego
- 代理机构: MPI IP Group
- 代理商 Kelly A. Echols; Herbert L. Ley, III
- 主分类号: A01N43/90
- IPC分类号: A01N43/90 ; A01N43/54 ; A61K31/519 ; A61K31/517 ; C07D413/00 ; C07D473/00 ; C07D401/00 ; C07D403/00 ; C07D417/00 ; C07D419/00 ; C07D239/72
摘要:
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
公开/授权文献
- US20050137213A1 Compounds and therapeutical use thereof 公开/授权日:2005-06-23
信息查询
IPC分类: