发明授权
- 专利标题： Method and apparatus for modifying tissue to improve electrical stimulation efficacy
- 专利标题（中）： 用于修饰组织以改善电刺激功效的方法和装置
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申请号： US11267654申请日： 2005-11-04
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公开(公告)号： US07630761B2公开(公告)日： 2009-12-08
- 发明人: Rodney W. Salo , Joseph M. Pastore , Haris J. Sih , Jihong Qu
- 申请人： Rodney W. Salo , Joseph M. Pastore , Haris J. Sih , Jihong Qu
- 申请人地址： US MN St. Paul
- 专利权人： Cardiac Pacemakers, Inc.
- 当前专利权人： Cardiac Pacemakers, Inc.
- 当前专利权人地址： US MN St. Paul
- 代理机构： Schwegman, Lundberg & Woessner, P.A.
- 主分类号： A61N1/18
- IPC分类号： A61N1/18
摘要：
A biologic agent delivery system provides for delivery of a biologic agent to a stimulation site to which electrical stimulation pulses are to be delivered from an electrical stimulation device. Examples of the electrical stimulation device include cardiac pacemakers and neural stimulators. The biologic agent modifies tissue property to lower the stimulation threshold of the stimulation site. The genetic modification of the tissue property improves efficacy and/or energy efficiency of an electrical stimulation therapy.
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