发明授权
US07632858B2 Open chain prolyl urea-related modulators of androgen receptor function
有权
开链脯氨酰脲相关调节剂的雄激素受体功能
- 专利标题： Open chain prolyl urea-related modulators of androgen receptor function
- 专利标题（中）： 开链脯氨酰脲相关调节剂的雄激素受体功能
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申请号： US10712456申请日： 2003-11-13
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公开(公告)号： US07632858B2公开(公告)日： 2009-12-15
- 发明人: Lawrence G. Hamann , David J. Augeri , Mark C. Manfredi
- 申请人： Lawrence G. Hamann , David J. Augeri , Mark C. Manfredi
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理机构： K & L Gates LLP
- 代理商 Stephanie Seidman; Frank J. Miskiel
- 主分类号： C07D207/12
- IPC分类号： C07D207/12 ; A61K31/4015 ; A61P35/00
摘要：
The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula I wherein R1, R2, R3, X, Y, Z and G are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia, and also provided are pharmaceutical compositions containing such compounds.
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