Invention Grant
US07642270B2 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
失效
5-氧代-5,8-二氢吡啶并嘧啶作为c-fms激酶的抑制剂
- Patent Title: 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
- Patent Title (中): 5-氧代-5,8-二氢吡啶并嘧啶作为c-fms激酶的抑制剂
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Application No.: US11519611Application Date: 2006-09-12
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Publication No.: US07642270B2Publication Date: 2010-01-05
- Inventor: Mark R. Player , Hui Huang , Daniel A. Hutta , Renee L. DesJarlais
- Applicant: Mark R. Player , Hui Huang , Daniel A. Hutta , Renee L. DesJarlais
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE Beerse
- Agent Thomas Dodd
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D471/06
Abstract:
The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof, wherein: W, A, Y, Z, R101 and R200 are described in the specification.
Public/Granted literature
- US20070060577A1 5-Oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase Public/Granted day:2007-03-15
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