发明授权
- 专利标题: Fused benzene derivative and use
- 专利标题(中): 熔融苯衍生物和使用
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申请号: US10524452申请日: 2003-08-11
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公开(公告)号: US07649001B2公开(公告)日: 2010-01-19
- 发明人: Mitsuru Shiraishi , Takahito Hara , Masami Kusaka , Naoyuki Kanzaki , Satoshi Yamamoto , Toshio Miyawaki
- 申请人: Mitsuru Shiraishi , Takahito Hara , Masami Kusaka , Naoyuki Kanzaki , Satoshi Yamamoto , Toshio Miyawaki
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理机构: Edwards Angell Palmer & Dodge LLP
- 代理商 David G. Conlin; Lisa Swiszcz Hazzard
- 优先权: JP2002-235275 20020812
- 国际申请: PCT/JP03/10228 WO 20030811
- 国际公布: WO2004/016576 WO 20040226
- 主分类号: A61K31/454
- IPC分类号: A61K31/454 ; C07D409/02
摘要:
The present invention provides a compound represented by the general formula: [wherein Ring A represents an optionally substituted 5- to 8-membered ring, Ring B represents a further optionally substituted 4- to 10-membered ring, Ring C represents a further optionally substituted benzene ring, X1 represents carbon atom, X2 represents a carbon atom, an oxygen atom, etc., W represents a nitrogen atom, etc., Y11 represents a group represented by the formula CR2R3′ (wherein R2 represents a hydrogen atom, a cyano group, a nitro group, etc., and R3′ represents a hydrogen atom, a cyano group, a nitro group, etc., respectively), Y21 represents a group represented by the formula CR4R5′ (wherein R4 represents a hydrogen atom, a cyano group, a nitro group, etc., and R5′ represents a hydrogen atom, a cyano group, a nitro group, etc., respectively), etc., and R1 represents an electron-withdrawing group, respectively. The formula represents a single bond or a double bond] or a salt thereof, which is useful as an androgen receptor modulator.
公开/授权文献
- US20060106067A1 Fused benzene derivative and use 公开/授权日:2006-05-18
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