发明授权
- 专利标题: Methods and apparatus for the regulation of hormone release
- 专利标题(中): 用于调节激素释放的方法和装置
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申请号: US11751813申请日: 2007-05-22
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公开(公告)号: US07650190B2公开(公告)日: 2010-01-19
- 发明人: Xiaohong Zhou , Thomas J. Mullen , Gary W. King , Michael R. S. Hill
- 申请人: Xiaohong Zhou , Thomas J. Mullen , Gary W. King , Michael R. S. Hill
- 申请人地址: US MN Minneapolis
- 专利权人: Medtronic, Inc.
- 当前专利权人: Medtronic, Inc.
- 当前专利权人地址: US MN Minneapolis
- 代理商 Stephen W. Bauer
- 主分类号: A61N1/00
- IPC分类号: A61N1/00
摘要:
A method and apparatus for delivering corrective therapy through hormone regulation is provided. Inhibition of sympathetic fibers by spinal cord stimulation is used to regulate the levels of hormones such as catecholamines, renin, and calcitonin gene-related peptide. The invention utilizes a closed or open loop feedback system in which physiological parameters such as the concentrations of hormones and sympathetic indicators such as heart rate and urine production are monitored and used to determine the appropriate level of neurostimulation. The site of electrical stimulation includes, but is not limited to, the spinal cord at levels T7-L2 and the associated neural fibers within a region of the T7-L2 dermatomes.