发明授权
- 专利标题： Variants of human glycoprotein hormone alpha chain: compositions and uses thereof
- 专利标题（中）： 人类糖蛋白激素α链的变体：其组成及用途
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申请号： US11429553申请日： 2006-05-05
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公开(公告)号： US07655781B2公开(公告)日： 2010-02-02
- 发明人: Ronen Shemesh , Jeanne Bernstein , Dvir Dahary , Gil Shalev , Gideon Baum , Yoseph Shaaltiel
- 申请人： Ronen Shemesh , Jeanne Bernstein , Dvir Dahary , Gil Shalev , Gideon Baum , Yoseph Shaaltiel
- 申请人地址： IL Tel Aviv IL Carmiel
- 专利权人： Compugen Ltd.,Protalix Ltd.
- 当前专利权人： Compugen Ltd.,Protalix Ltd.
- 当前专利权人地址： IL Tel Aviv IL Carmiel
- 代理机构： Winston & Strawn LLP
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12N15/16 ; C12P21/02 ; C12N15/05 ; A61K38/24
摘要：
The present invention provides human glycoprotein hormone (hGPH) α-chain splice variants, including isolated nucleic acids encoding these variants and the encoded amino acid sequences, as well as antibodies, antisense oligonucleotides, expression vectors and host cells comprising these sequences. The present invention further discloses the use of these sequences in the diagnosis, prevention and treatment of symptoms, diseases and disorders related to glycoprotein hormones.
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