A liquid crystal display (LCD) panel, including a first substrate, a second substrate, a liquid crystal layer, a patterned sealant, several first stop structures, several second stop structures and several seal spacers, is provided. The first substrate is opposite to the second substrate. The liquid crystal layer and the patterned sealant surrounding it are disposed between the first substrate and the second substrate. The first stop structures disposed inside the patterned sealant surround the liquid crystal layer. Each second stop structure disposed inside the patterned sealant is located next to one of the first stop structures. The height H1 of each first or second stop structure is smaller than the distance H2 between the first and second substrates. The seal spacers are disposed inside the patterned sealant and located between the first and the second stop structures. A manufacture method of the LCD panel thereof is further provided.