Invention Grant
US07662808B2 Diazabicyclic aryl derivatives as cholinergic receptor modulators
失效
二氮杂双环芳基衍生物作为胆碱能受体调节剂
- Patent Title: Diazabicyclic aryl derivatives as cholinergic receptor modulators
- Patent Title (中): 二氮杂双环芳基衍生物作为胆碱能受体调节剂
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Application No.: US10586836Application Date: 2005-02-01
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Publication No.: US07662808B2Publication Date: 2010-02-16
- Inventor: Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Tino Dyhring Jørgensen , Daniel B Timmermann
- Applicant: Dan Peters , Gunnar M. Olsen , Elsebet Østergaard Nielsen , Tino Dyhring Jørgensen , Daniel B Timmermann
- Applicant Address: DK Ballerup
- Assignee: NeuroSearch A/S
- Current Assignee: NeuroSearch A/S
- Current Assignee Address: DK Ballerup
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: DK200400171 20040204; DK200400812 20040524
- International Application: PCT/EP2005/050404 WO 20050201
- International Announcement: WO2005/074940 WO 20050818
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A61K31/33 ; C07D487/00
Abstract:
This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemicals substances.
Public/Granted literature
- US20080227773A1 Diazabicyclic Aryl Derivatives as Cholinergic Receptor Modulators Public/Granted day:2008-09-18
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