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US07662915B2 Peptides having protected amines of untargeted sites, methods for production thereof and of specifically conjugated PEG peptides using the same 有权
具有非靶向位点的保护胺的肽,其制备方法和使用其的特异性缀合的PEG肽

Peptides having protected amines of untargeted sites, methods for production thereof and of specifically conjugated PEG peptides using the same
Abstract:
The present invention relates to synthetic peptides having selectively protected amines of untargeted sites and to methods for production thereof and for specifically conjugating PEG to targeted sites of the synthetic peptides using the same. The present invention provides a much higher yield of PEG conjugated peptides in which PEG is specifically combined to amines at targeted sites.
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