发明授权
- 专利标题： siRNA targeting connective tissue growth factor (CTGF)
- 专利标题（中）： siRNA靶向结缔组织生长因子（CTGF）
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申请号： US12321749申请日： 2009-01-23
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公开(公告)号： US07666853B2公开(公告)日： 2010-02-23
- 发明人: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- 申请人： Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- 申请人地址： US CO Lafayette
- 专利权人： Dharmacon, Inc.
- 当前专利权人： Dharmacon, Inc.
- 当前专利权人地址： US CO Lafayette
- 代理机构： Kalow & Springut, LLP
- 代理商 Scott D. Locke, Esq.
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/02 ; C07H21/04
摘要：
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to CTGF.
公开/授权文献
- US20090191625A1 siRNA targeting connective tissue growth factor (CTGF) 公开/授权日：2009-07-30