Invention Grant
US07666888B2 Substituted azole aromatic heterocycles as inhibitors of 11β-HSD-1
失效
取代的唑类芳族杂环作为11＆amp; bgr-HSD-1的抑制剂
- Patent Title: Substituted azole aromatic heterocycles as inhibitors of 11β-HSD-1
- Patent Title (中): 取代的唑类芳族杂环作为11＆amp; bgr-HSD-1的抑制剂
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Application No.: US11779599Application Date: 2007-07-18
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Publication No.: US07666888B2Publication Date: 2010-02-23
- Inventor: Michael D. Bartberger , Christopher H. Fotsch , Martin Haraldsson , David St. Jean , Lars Johansson , Marianne Nilsson , Lori Sutin , Katrina Flyrén
- Applicant: Michael D. Bartberger , Christopher H. Fotsch , Martin Haraldsson , David St. Jean , Lars Johansson , Marianne Nilsson , Lori Sutin , Katrina Flyrén
- Applicant Address: US CA Thousand Oaks SE Stockholm
- Assignee: Amgen Inc.,Biovitrum AB
- Current Assignee: Amgen Inc.,Biovitrum AB
- Current Assignee Address: US CA Thousand Oaks SE Stockholm
- Agency: Foley & Lardner LLP
- Main IPC: A61K31/422
- IPC: A61K31/422 ; A61K31/4155 ; C07D261/06 ; C07D231/10
Abstract:
Compounds of formula I and IV are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorder: wherein the variables A-B, R1, R2, m, and Q are described herein.
Public/Granted literature
- US20080021022A1 SUBSTITUTED AZOLE AROMATIC HETEROCYCLES AS INHIBITORS OF 11BETA-HSD-1 Public/Granted day:2008-01-24
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