发明授权
- 专利标题: Cinnamide compound
- 专利标题(中): 桂酰胺化合物
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申请号: US11136355申请日: 2005-05-25
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公开(公告)号: US07667041B2公开(公告)日: 2010-02-23
- 发明人: Teiji Kimura , Koki Kawano , Eriko Doi , Noritaka Kitazawa , Kogyoku Shin , Takehiko Miyagawa , Toshihiko Kaneko , Koichi Ito , Mamoru Takaishi , Hiroaki Hagiwara
- 申请人: Teiji Kimura , Koki Kawano , Eriko Doi , Noritaka Kitazawa , Kogyoku Shin , Takehiko Miyagawa , Toshihiko Kaneko , Koichi Ito , Mamoru Takaishi , Hiroaki Hagiwara
- 申请人地址: JP Tokyo
- 专利权人: Eisai R&D Management Co., Ltd.
- 当前专利权人: Eisai R&D Management Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: JP2004-155790 20040526; JP2004-310909 20041026
- 主分类号: C07D401/00
- IPC分类号: C07D401/00 ; A61K31/54
摘要:
The present invention relates to a compound represented by Formula (I): (wherein Ar1 represents an imidazolyl group which may be substituted with 1 to 3 substituents; Ar2 represents a pyridinyl group, a pyrimidinyl group, or a phenyl group which may be substituted with 1 to 3 substituents; X1 represents (1) —C≡C— or (2) a double bond etc. which may be substituted; R1 and R2 represent, for example, a C1-6 alkyl group or C3-8 cycloalkyl group which may be substituted) or a pharmacologically acceptable salt thereof and to the use thereof as pharmaceutical agents. The object of the present invention is to find a therapeutic or preventive agent for diseases caused by Aβ. According to the present invention, a therapeutic or preventive agents for diseases caused by Aβ can be provided.
公开/授权文献
- US20060004013A1 Cinnamide compound 公开/授权日:2006-01-05